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Calpain Inhibition Modulates GSK-3β Pathways in Ischemic Myocardium: A Proteomic and Mechanistic Analysis
OBJECTIVES: Calpain inhibition has an enhancing effect on myocardial perfusion and improves myocardial density by up regulating by inhibition of GSK-3β and up regulating downstream signaling pathways including the insulin/PI3K and WNT/β-catenin pathways in a pig model of chronic myocardial ischemia...
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| Udgivet i: | J Thorac Cardiovasc Surg |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5250534/ https://ncbi.nlm.nih.gov/pubmed/27986275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2016.09.087 |
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