Effects of avitinib on the pharmacokinetics of osimertinib in vitro and in vivo in rats

BACKGROUND: Avitinib is one type of the third‐generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) for the treatment of non‐small cell lung cancer (NSCLC) with EGFR mutations. The purpose of this study was to investigate the effect of avitinib on the pharmacokinetics...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Thorac Cancer
Autori principali: Wu, Qingjun, Jiang, Hui, Wang, Shuanghu, Dai, Dapeng, Chen, Feifei, Meng, Deru, Geng, Peiwu, Tong, Hongfeng, Zhou, Yunfang, Pan, Debiao, Zhou, Quan, Wang, Chunjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons Australia, Ltd 2020
Soggetti:
Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529555/
https://ncbi.nlm.nih.gov/pubmed/32812378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1759-7714.13587
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