Inhibitory Effect of Imperatorin on the Pharmacokinetics of Diazepam In Vitro and In Vivo

BACKGROUND: Diazepam is a benzodiazepine drug used to treat anxiety, insomnia, and muscle spasms. Imperatorin is a phytochemical isolated from medicinal plants and is widely used in herbal medicine. The aim of this study was to investigate the interactions between imperatorin and diazepam in vitro a...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Zhou, Yunfang, Meng, Deru, Chen, Feifei, Wu, Zhengping, Wang, Binglan, Wang, Shuanghu, Geng, Peiwu, Dai, Dapeng, Zhou, Quan, Qiu, Weiwen
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525091/
https://ncbi.nlm.nih.gov/pubmed/33041783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01079
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