Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth

The umbilical artery lumen closes rapidly at birth, preventing neonatal blood loss, whereas the umbilical vein remains patent longer. Here, analysis of umbilical cords from humans and other mammals identified differential arterial-venous proteoglycan dynamics as a determinant of these contrasting va...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Nandadasa, Sumeda, Szafron, Jason M, Pathak, Vai, Murtada, Sae-Il, Kraft, Caroline M, O'Donnell, Anna, Norvik, Christian, Hughes, Clare, Caterson, Bruce, Domowicz, Miriam S, Schwartz, Nancy B, Tran-Lundmark, Karin, Veigl, Martina, Sedwick, David, Philipson, Elliot H, Humphrey, Jay D, Apte, Suneel S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2020
Aiheet:
Computational and Systems Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529456/
https://ncbi.nlm.nih.gov/pubmed/32909945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60683
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