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Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice

Cognitive decline with age is a harmful process that can reduce quality of life. Multiple factors have been established to contribute to cognitive decline, but the overall etiology remains unknown. Here, we hypothesized that cognitive dysfunction is mediated, in part, by increased levels of inflamma...

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Bibliografiset tiedot
Julkaisussa:J Lipid Res
Päätekijät: Parks, Eileen E., Logan, Sreemathi, Yeganeh, Alexander, Farley, Julie A., Owen, Daniel B., Sonntag, William E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Biochemistry and Molecular Biology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529050/
https://ncbi.nlm.nih.gov/pubmed/32669383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000479
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