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Interleukin 6 reduces allopregnanolone synthesis in the brain and contributes to age-related cognitive decline in mice

Cognitive decline with age is a harmful process that can reduce quality of life. Multiple factors have been established to contribute to cognitive decline, but the overall etiology remains unknown. Here, we hypothesized that cognitive dysfunction is mediated, in part, by increased levels of inflamma...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Parks, Eileen E., Logan, Sreemathi, Yeganeh, Alexander, Farley, Julie A., Owen, Daniel B., Sonntag, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529050/
https://ncbi.nlm.nih.gov/pubmed/32669383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000479
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