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Intranasal Leptin Prevents Opioid-induced Sleep-disordered Breathing in Obese Mice
Respiratory depression is the main cause of morbidity and mortality associated with opioids. Obesity increases opioid-related mortality, which is mostly related to comorbid obstructive sleep apnea. Naloxone, a μ-opioid receptor blocker, is an effective antidote, but it reverses analgesia. Like human...
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| 出版年: | Am J Respir Cell Mol Biol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Thoracic Society
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7528928/ https://ncbi.nlm.nih.gov/pubmed/32603263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2020-0117OC |
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