TGF-β and Eomes control the homeostasis of CD8(+) regulatory T cells

In addition to Foxp3(+) CD4(+) regulatory T cells (CD4(+) T reg cells), Foxp3(−) CD8(+) regulatory T cells (CD8(+) T reg cells) are critical to maintain immune tolerance. However, the molecular programs that specifically control CD8(+) but not CD4(+) T reg cells are largely unknown. Here, we demonst...

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Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Mishra, Shruti, Liao, Wei, Liu, Yong, Yang, Ming, Ma, Chaoyu, Wu, Haijing, Zhao, Ming, Zhang, Xin, Qiu, Yuanzheng, Lu, Qianjin, Zhang, Nu
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527976/
https://ncbi.nlm.nih.gov/pubmed/32991667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200030
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