Activation of 4-1BBL(+) B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma

Immunotherapy has revolutionized the treatment of many tumors. However, most glioblastoma (GBM) patients have not, so far, benefited from such successes. With the goal of exploring ways to boost anti-GBM immunity, we developed a B cell–based vaccine (B(Vax)) that consists of 4-1BBL(+) B cells activa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Lee-Chang, Catalina, Miska, Jason, Hou, David, Rashidi, Aida, Zhang, Peng, Burga, Rachel A., Jusué-Torres, Ignacio, Xiao, Ting, Arrieta, Victor A., Zhang, Daniel Y., Lopez-Rosas, Aurora, Han, Yu, Sonabend, Adam M., Horbinski, Craig M., Stupp, Roger, Balyasnikova, Irina V., Lesniak, Maciej S.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527974/
https://ncbi.nlm.nih.gov/pubmed/32991668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200913
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados