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Polyunsaturated fatty acid biosynthesis pathway and genetics. implications for interindividual variability in prothrombotic, inflammatory conditions such as COVID-19(✰,✰✰,★,★★)

COVID-19 symptoms vary from silence to rapid death, the latter mediated by both a cytokine storm and a thrombotic storm. SARS-CoV (2003) induces Cox-2, catalyzing the synthesis, from highly unsaturated fatty acids (HUFA), of eicosanoids and docosanoids that mediate both inflammation and thrombosis....

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Detalhes bibliográficos
Publicado no:Prostaglandins Leukot Essent Fatty Acids
Main Authors: Kothapalli, Kumar S.D., Park, Hui Gyu, Brenna, J. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527828/
https://ncbi.nlm.nih.gov/pubmed/33038834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2020.102183
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