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Desaturase and elongase limiting endogenous long chain polyunsaturated fatty acid biosynthesis

PURPOSE OF REVIEW: Endogenous synthesis of the long chain polyunsaturated fatty acids (LCPUFA) is mediated by the fatty acid desaturase (FADS) gene cluster (11q12-13.1) and elongation of very long chain fatty acids 2 (ELOVL2) (6p24.2) and ELOVL5 (6p12.1). Though older biochemical work identified the...

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Bibliographic Details
Published in:Curr Opin Clin Nutr Metab Care
Main Authors: Zhang, Ji Yao, Kothapalli, Kumar S.D., Brenna, J. Thomas
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768719/
https://ncbi.nlm.nih.gov/pubmed/26828581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MCO.0000000000000254
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