Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy

Cardiovascular and renal complications are the predominant causes of morbidity and mortality amongst patients with diabetes. Development of novel treatments have been hampered by the lack of available animal models recapitulating the human disease. We hypothesized that experimental diabetes in rats...

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izdano v:Sci Rep
Main Authors: Thisted, Louise, Østergaard, Mette V., Pedersen, Annemarie A., Pedersen, Philip J., Lindsay, Ross T., Murray, Andrew J., Fink, Lisbeth N., Pedersen, Tanja X., Secher, Thomas, Johansen, Thea T., Thrane, Sebastian T., Skarsfeldt, Torben, Jelsing, Jacob, Thomsen, Morten B., Zois, Nora E.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527487/
https://ncbi.nlm.nih.gov/pubmed/32999377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73046-8
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