Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model

Uncontrolled activation of transforming growth factor beta (TGF-β) family members is hypothesized to participate in type 2 diabetes (T2D) dependent diabetic nephropathy (DN). We evaluated and compared downstream activation of the Smad2-signaling pathway in kidney samples from T2D patients to kidneys...

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Dades bibliogràfiques
Publicat a:Ren Fail
Autors principals: Thomsen, Lise Høj, Fog-Tonnesen, Morten, Nielsen Fink, Lisbeth, Norlin, Jenny, García de Vinuesa, Amaya, Hansen, Troels Krarup, de Heer, Emile, ten Dijke, Peter, Rosendahl, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Laboratory Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446227/
https://ncbi.nlm.nih.gov/pubmed/28805484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0886022X.2017.1361837
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