Disparate phospho-Smad2 levels in advanced type 2 diabetes patients with diabetic nephropathy and early experimental db/db mouse model

Uncontrolled activation of transforming growth factor beta (TGF-β) family members is hypothesized to participate in type 2 diabetes (T2D) dependent diabetic nephropathy (DN). We evaluated and compared downstream activation of the Smad2-signaling pathway in kidney samples from T2D patients to kidneys...

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Detalles Bibliográficos
Publicado en:Ren Fail
Main Authors: Thomsen, Lise Høj, Fog-Tonnesen, Morten, Nielsen Fink, Lisbeth, Norlin, Jenny, García de Vinuesa, Amaya, Hansen, Troels Krarup, de Heer, Emile, ten Dijke, Peter, Rosendahl, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Laboratory Study
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446227/
https://ncbi.nlm.nih.gov/pubmed/28805484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0886022X.2017.1361837
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