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Probing single-cell metabolism reveals prognostic value of highly metabolically active circulating stromal cells in prostate cancer

Despite their important role in metastatic disease, no general method to detect circulating stromal cells (CStCs) exists. Here, we present the Metabolic Assay-Chip (MA-Chip) as a label-free, droplet-based microfluidic approach allowing single-cell extracellular pH measurement for the detection and i...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Rivello, Francesca, Matuła, Kinga, Piruska, Aigars, Smits, Minke, Mehra, Niven, Huck, Wilhelm T. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527228/
https://ncbi.nlm.nih.gov/pubmed/32998889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz3849
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