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3D microniches reveal the importance of cell size and shape

Geometrical cues have been shown to alter gene expression and differentiation on 2D substrates. However, little is known about how geometrical cues affect cell function in 3D. One major reason for this lack of understanding is rooted in the difficulties of controlling cell geometry in a complex 3D s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bao, Min, Xie, Jing, Piruska, Aigars, Huck, Wilhelm T. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719012/
https://ncbi.nlm.nih.gov/pubmed/29213086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02163-2
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