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Probing single-cell metabolism reveals prognostic value of highly metabolically active circulating stromal cells in prostate cancer

Despite their important role in metastatic disease, no general method to detect circulating stromal cells (CStCs) exists. Here, we present the Metabolic Assay-Chip (MA-Chip) as a label-free, droplet-based microfluidic approach allowing single-cell extracellular pH measurement for the detection and i...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Adv
Hauptverfasser: Rivello, Francesca, Matuła, Kinga, Piruska, Aigars, Smits, Minke, Mehra, Niven, Huck, Wilhelm T. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527228/
https://ncbi.nlm.nih.gov/pubmed/32998889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz3849
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