Complex Rab4-mediated regulation of endosomal size and EGFR activation

Early sorting endosomes are responsible for the trafficking and function of transferrin receptor (TfR) and epidermal growth factor receptor (EGFR). These receptors play important roles in iron uptake and signaling and are critical for breast cancer development. However, the role of morphology, recep...

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Publicat a:Mol Cancer Res
Autors principals: Tubbesing, Kate, Ward, Jamie, Abini-Agbomson, Ray, Malhotra, Aditi, Rudkouskaya, Alena, Warren, Janine, Lamar, John, Martino, Nina, Adam, Alejandro P., Barroso, Margarida
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526990/
https://ncbi.nlm.nih.gov/pubmed/32019812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0052
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