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Complex Rab4-mediated regulation of endosomal size and EGFR activation

Early sorting endosomes are responsible for the trafficking and function of transferrin receptor (TfR) and epidermal growth factor receptor (EGFR). These receptors play important roles in iron uptake and signaling and are critical for breast cancer development. However, the role of morphology, recep...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Tubbesing, Kate, Ward, Jamie, Abini-Agbomson, Ray, Malhotra, Aditi, Rudkouskaya, Alena, Warren, Janine, Lamar, John, Martino, Nina, Adam, Alejandro P., Barroso, Margarida
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526990/
https://ncbi.nlm.nih.gov/pubmed/32019812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0052
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