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Quantitative Imaging of Receptor-Ligand Engagement in Intact Live Animals

Maintaining an intact tumor environment is critical for quantitation of receptor-ligand engagement in a targeted drug development pipeline. However, measuring receptor-ligand engagement in vivo and non-invasively in preclinical settings is extremely challenging. We found that quantitation of intrace...

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Bibliografski detalji
Izdano u:J Control Release
Glavni autori: Rudkouskaya, Alena, Sinsuebphon, Nattawut, Ward, Jamie, Tubbesing, Kate, Intes, Xavier, Barroso, Margarida
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231501/
https://ncbi.nlm.nih.gov/pubmed/30036545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.07.032
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