Fast fit-free analysis of fluorescence lifetime imaging via deep learning

Fluorescence lifetime imaging (FLI) provides unique quantitative information in biomedical and molecular biology studies but relies on complex data-fitting techniques to derive the quantities of interest. Herein, we propose a fit-free approach in FLI image formation that is based on deep learning (D...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Smith, Jason T., Yao, Ruoyang, Sinsuebphon, Nattawut, Rudkouskaya, Alena, Un, Nathan, Mazurkiewicz, Joseph, Barroso, Margarida, Yan, Pingkun, Intes, Xavier
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883809/
https://ncbi.nlm.nih.gov/pubmed/31719196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912707116
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