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Quantification of Trastuzumab–HER2 Engagement In Vitro and In Vivo

Human EGF Receptor 2 (HER2) is an important oncogene driving aggressive metastatic growth in up to 20% of breast cancer tumors. At the same time, it presents a target for passive immunotherapy such as trastuzumab (TZM). Although TZM has been widely used clinically since 1998, not all eligible patien...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Rudkouskaya, Alena, Smith, Jason T., Intes, Xavier, Barroso, Margarida
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767145/
https://ncbi.nlm.nih.gov/pubmed/33348564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25245976
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