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In Vitro Activity of Manogepix (APX001A) and Comparators against Contemporary Molds: MEC Comparison and Preliminary Experience with Colorimetric MIC Determination

Manogepix (APX001A) is the active moiety of the drug candidate fosmanogepix (APX001), currently in clinical development for the treatment of invasive fungal infections. We compared manogepix EUCAST minimum effective concentrations (MECs) to MICs of five comparators and CLSI MECs and MICs by a colori...

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發表在:Antimicrob Agents Chemother
Main Authors: Jørgensen, Karin Meinike, Astvad, Karen M. T., Arendrup, Maiken Cavling
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526828/
https://ncbi.nlm.nih.gov/pubmed/32513793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00730-20
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