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In Vitro Activity of Manogepix (APX001A) and Comparators against Contemporary Molds: MEC Comparison and Preliminary Experience with Colorimetric MIC Determination

Manogepix (APX001A) is the active moiety of the drug candidate fosmanogepix (APX001), currently in clinical development for the treatment of invasive fungal infections. We compared manogepix EUCAST minimum effective concentrations (MECs) to MICs of five comparators and CLSI MECs and MICs by a colori...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jørgensen, Karin Meinike, Astvad, Karen M. T., Arendrup, Maiken Cavling
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526828/
https://ncbi.nlm.nih.gov/pubmed/32513793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00730-20
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