In Vitro Activity of Manogepix (APX001A) and Comparators against Contemporary Molds: MEC Comparison and Preliminary Experience with Colorimetric MIC Determination

Manogepix (APX001A) is the active moiety of the drug candidate fosmanogepix (APX001), currently in clinical development for the treatment of invasive fungal infections. We compared manogepix EUCAST minimum effective concentrations (MECs) to MICs of five comparators and CLSI MECs and MICs by a colori...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Jørgensen, Karin Meinike, Astvad, Karen M. T., Arendrup, Maiken Cavling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2020
Gaiak:
Susceptibility
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526828/
https://ncbi.nlm.nih.gov/pubmed/32513793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00730-20
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