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In Vitro Activity of Manogepix (APX001A) and Comparators against Contemporary Molds: MEC Comparison and Preliminary Experience with Colorimetric MIC Determination

Manogepix (APX001A) is the active moiety of the drug candidate fosmanogepix (APX001), currently in clinical development for the treatment of invasive fungal infections. We compared manogepix EUCAST minimum effective concentrations (MECs) to MICs of five comparators and CLSI MECs and MICs by a colori...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Jørgensen, Karin Meinike, Astvad, Karen M. T., Arendrup, Maiken Cavling
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526828/
https://ncbi.nlm.nih.gov/pubmed/32513793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00730-20
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