Structure-Activity Relationship Analysis of Benzotriazine Analogues as HIV-1 Latency-Reversing Agents

“Shock and kill” therapeutic strategies toward HIV eradication are based on the transcriptional activation of latent HIV with a latency-reversing agent (LRA) and the consequent killing of the reactivated cell by either the cytopathic effect of HIV or an arm of the immune system. We have recently fou...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Sorensen, Eric S., Macedo, Amanda B., Resop, Rachel S., Howard, J. Natalie, Nell, Racheal, Sarabia, Indra, Newman, Daniel, Ren, Yanqin, Jones, R. Brad, Planelles, Vicente, Spivak, Adam M., Bosque, Alberto
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526807/
https://ncbi.nlm.nih.gov/pubmed/32482680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00888-20
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