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Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients

The human immunodeficiency virus type 1 (HIV-1) latent reservoir in resting CD4(+) T cells represents a major barrier to viral eradication. Small compounds capable of latency reversal have not demonstrated uniform responses across in vitro HIV-1 latency cell models. Characterizing compounds that dem...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Spivak, Adam M., Bosque, Alberto, Balch, Alfred H., Smyth, David, Martins, Laura, Planelles, Vicente
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576101/
https://ncbi.nlm.nih.gov/pubmed/26169416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01077-15
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