Amlodipine Increases the Therapeutic Potential of Ravuconazole upon Trypanosoma cruzi Infection

Mining existing agents that enhance the therapeutic potential of ergosterol biosynthesis inhibitors (EBI) is a promising approach to improve Chagas disease chemotherapy. In this study, we evaluated the effect of ravuconazole, an EBI, combined with amlodipine, a calcium channel blocker, upon Trypanos...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Machado, Yara Almeida, Bahia, Maria Terezinha, Caldas, Ivo Santana, Mazzeti, Ana Lia, Novaes, Rômulo Dias, Vilas Boas, Breno Raimundo, Santos, Lorena Júnia de Souza, Martins-Filho, Olindo Assis, Marques, Marcos José, Diniz, Lívia de Figueiredo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526806/
https://ncbi.nlm.nih.gov/pubmed/32423960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02497-19
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