Ravuconazole self-emulsifying delivery system: in vitro activity against Trypanosoma cruzi amastigotes and in vivo toxicity

Self-emulsifying drug delivery systems (SEDDSs) are lipid-based anhydrous formulations composed of an isotropic mixture of oil, surfactant, and cosurfactants usually presented in gelatin capsules. Ravuconazole (Biopharmaceutics Classification System [BCS] Class II) is a poorly water-soluble drug, an...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Spósito, Pollyanna Álvaro, Mazzeti, Ana Lia, de Oliveira Faria, Caroline, Urbina, Julio A, Pound-Lana, Gwenaelle, Bahia, Maria Terezinha, Mosqueira, Vanessa Furtado
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439725/
https://ncbi.nlm.nih.gov/pubmed/28553114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S133708
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