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Outcome of E1224-Benznidazole Combination Treatment for Infection with a Multidrug-Resistant Trypanosoma cruzi Strain in Mice

Combination therapy has been proposed as an alternative therapeutic approach for the treatment of Chagas disease. In this study, we evaluated the effect of treatment with benznidazole combined with E1224 (ravuconazole prodrug) in an experimental murine model of acute infection. The first set of expe...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Diniz, Lívia de Figueiredo, Mazzeti, Ana Lia, Caldas, Ivo Santana, Ribeiro, Isabela, Bahia, Maria Terezinha
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971593/
https://ncbi.nlm.nih.gov/pubmed/29555633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00401-18
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