AR-12 Exhibits Direct and Host-Targeted Antibacterial Activity toward Mycobacterium abscessus

Therapeutic options for Mycobacterium abscessus infections are extremely limited. New or repurposed drugs are needed. The anti-M. abscessus activity of AR-12 (OSU-03012), reported to express broad-spectrum antimicrobial effects, was investigated in vitro and in vivo. Antimicrobial susceptibility tes...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Zhang, Shaoyan, Zou, Yuzhen, Guo, Qi, Chen, Jianhui, Xu, Liyun, Wan, Xiaoyu, Zhang, Zhemin, Li, Bing, Chu, Haiqing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Susceptibility
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526805/
https://ncbi.nlm.nih.gov/pubmed/32482678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00236-20
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