Genetic Evolution of Mycobacterium abscessus Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy

OBJECTIVES: Clarithromycin is recommended as the core agent for treating M. abscessus infections, which usually calls for at least one year of treatment course, facilitating the development of resistance. This study aimed to identify the underlying mechanism of in vivo development of clarithromycin...

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Опубликовано в: :Can Respir J
Главные авторы: Li, Bing, Guo, Qi, Mao, Yanhua, Zou, Yuzhen, Zhang, Yongjie, Zhang, Zhemin, Chu, Haiqing
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142343/
https://ncbi.nlm.nih.gov/pubmed/32300380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7623828
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