Efflux Pumps Contribute to Intrinsic Clarithromycin Resistance in Clinical, Mycobacterium abscessus Isolates

PURPOSE: The emergence of clarithromycin resistance is a challenge in treating Mycobacterium abscessus infections. Known mechanisms that contribute to intrinsic clarithromycin resistance focus on rrl gene-related mutations, but resistant clinical isolates often exhibit an inconsistent rrl genotype....

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Enregistré dans:
Détails bibliographiques
Publié dans:Infect Drug Resist
Auteurs principaux: Guo, Qi, Chen, Jianhui, Zhang, Shaoyan, Zou, Yuzhen, Zhang, Yongjie, Huang, Dongdong, Zhang, Zhemin, Li, Bing, Chu, Haiqing
Format: Artigo
Langue:Inglês
Publié: Dove 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024787/
https://ncbi.nlm.nih.gov/pubmed/32104016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S239850
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