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Genetic Evolution of Mycobacterium abscessus Conferring Clarithromycin Resistance during Long-Term Antibiotic Therapy

OBJECTIVES: Clarithromycin is recommended as the core agent for treating M. abscessus infections, which usually calls for at least one year of treatment course, facilitating the development of resistance. This study aimed to identify the underlying mechanism of in vivo development of clarithromycin...

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Detalhes bibliográficos
Publicado no:Can Respir J
Main Authors: Li, Bing, Guo, Qi, Mao, Yanhua, Zou, Yuzhen, Zhang, Yongjie, Zhang, Zhemin, Chu, Haiqing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142343/
https://ncbi.nlm.nih.gov/pubmed/32300380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7623828
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