TRPV4 antagonists ameliorate ventriculomegaly in a rat model of hydrocephalus

Hydrocephalus is a serious condition that impacts patients of all ages. The standards of care are surgical options to divert, or inhibit production of, cerebrospinal fluid; to date, there are no effective pharmaceutical treatments, to our knowledge. The causes vary widely, but one commonality of thi...

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Опубликовано в: :JCI Insight
Главные авторы: Hochstetler, Alexandra E., Smith, Hillary M., Preston, Daniel C., Reed, Makenna M., Territo, Paul R., Shim, Joon W., Fulkerson, Daniel, Blazer-Yost, Bonnie L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526552/
https://ncbi.nlm.nih.gov/pubmed/32938829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137646
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