IL-32γ potentiates tumor immunity in melanoma

Myeloid cells orchestrate the antitumor immune response and influence the efficacy of immune checkpoint blockade (ICB) therapies. We and others have previously shown that IL-32 mediates DC differentiation and macrophage activation. Here, we demonstrate that IL-32 expression in human melanoma positiv...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Gruber, Thomas, Kremenovic, Mirela, Sadozai, Hassan, Rombini, Nives, Baeriswyl, Lukas, Maibach, Fabienne, Modlin, Robert L., Gilliet, Michel, von Werdt, Diego, Hunger, Robert E., Seyed Jafari, S. Morteza, Parisi, Giulia, Abril-Rodriguez, Gabriel, Ribas, Antoni, Schenk, Mirjam
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526542/
https://ncbi.nlm.nih.gov/pubmed/32841222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138772
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