IL-32γ potentiates tumor immunity in melanoma

Myeloid cells orchestrate the antitumor immune response and influence the efficacy of immune checkpoint blockade (ICB) therapies. We and others have previously shown that IL-32 mediates DC differentiation and macrophage activation. Here, we demonstrate that IL-32 expression in human melanoma positiv...

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Foilsithe in:JCI Insight
Main Authors: Gruber, Thomas, Kremenovic, Mirela, Sadozai, Hassan, Rombini, Nives, Baeriswyl, Lukas, Maibach, Fabienne, Modlin, Robert L., Gilliet, Michel, von Werdt, Diego, Hunger, Robert E., Seyed Jafari, S. Morteza, Parisi, Giulia, Abril-Rodriguez, Gabriel, Ribas, Antoni, Schenk, Mirjam
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2020
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526542/
https://ncbi.nlm.nih.gov/pubmed/32841222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138772
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