IL-32γ potentiates tumor immunity in melanoma

Myeloid cells orchestrate the antitumor immune response and influence the efficacy of immune checkpoint blockade (ICB) therapies. We and others have previously shown that IL-32 mediates DC differentiation and macrophage activation. Here, we demonstrate that IL-32 expression in human melanoma positiv...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Gruber, Thomas, Kremenovic, Mirela, Sadozai, Hassan, Rombini, Nives, Baeriswyl, Lukas, Maibach, Fabienne, Modlin, Robert L., Gilliet, Michel, von Werdt, Diego, Hunger, Robert E., Seyed Jafari, S. Morteza, Parisi, Giulia, Abril-Rodriguez, Gabriel, Ribas, Antoni, Schenk, Mirjam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526542/
https://ncbi.nlm.nih.gov/pubmed/32841222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138772
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