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Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained viral dissemination and organ injury. A key explanation...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Remy, Kenneth E., Mazer, Monty, Striker, David A., Ellebedy, Ali H., Walton, Andrew H., Unsinger, Jacqueline, Blood, Teresa M., Mudd, Philip A., Yi, Daehan J., Mannion, Daniel A., Osborne, Dale F., Martin, R. Scott, Anand, Nitin J., Bosanquet, James P., Blood, Jane, Drewry, Anne M., Caldwell, Charles C., Turnbull, Isaiah R., Brakenridge, Scott C., Moldwawer, Lyle L., Hotchkiss, Richard S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526441/
https://ncbi.nlm.nih.gov/pubmed/32687484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140329
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