Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

COVID-19–associated morbidity and mortality have been attributed to a pathologic host response. Two divergent hypotheses have been proposed: hyperinflammatory cytokine storm; and failure of host protective immunity that results in unrestrained viral dissemination and organ injury. A key explanation...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Remy, Kenneth E., Mazer, Monty, Striker, David A., Ellebedy, Ali H., Walton, Andrew H., Unsinger, Jacqueline, Blood, Teresa M., Mudd, Philip A., Yi, Daehan J., Mannion, Daniel A., Osborne, Dale F., Martin, R. Scott, Anand, Nitin J., Bosanquet, James P., Blood, Jane, Drewry, Anne M., Caldwell, Charles C., Turnbull, Isaiah R., Brakenridge, Scott C., Moldwawer, Lyle L., Hotchkiss, Richard S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526441/
https://ncbi.nlm.nih.gov/pubmed/32687484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140329
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