Loading...

ANGPTL8 has both endocrine and autocrine effects on substrate utilization

The angiopoietin-like protein ANGPTL8 (A8) is one of 3 ANGPTLs (A8, A3, A4) that coordinate changes in triglyceride (TG) delivery to tissues by inhibiting lipoprotein lipase (LPL), an enzyme that hydrolyzes TG. Previously we showed that A8, which is expressed in liver and adipose tissue, is required...

Full description

Saved in:
Bibliographic Details
Published in:JCI Insight
Main Authors: Oldoni, Federico, Cheng, Haili, Banfi, Serena, Gusarova, Viktoria, Cohen, Jonathan C., Hobbs, Helen H.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526440/
https://ncbi.nlm.nih.gov/pubmed/32730227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138777
Tags: Add Tag
No Tags, Be the first to tag this record!