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ANGPTL8 has both endocrine and autocrine effects on substrate utilization

The angiopoietin-like protein ANGPTL8 (A8) is one of 3 ANGPTLs (A8, A3, A4) that coordinate changes in triglyceride (TG) delivery to tissues by inhibiting lipoprotein lipase (LPL), an enzyme that hydrolyzes TG. Previously we showed that A8, which is expressed in liver and adipose tissue, is required...

詳細記述

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書誌詳細
出版年:JCI Insight
主要な著者: Oldoni, Federico, Cheng, Haili, Banfi, Serena, Gusarova, Viktoria, Cohen, Jonathan C., Hobbs, Helen H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526440/
https://ncbi.nlm.nih.gov/pubmed/32730227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138777
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