Hepatic ANGPTL3 regulates adipose tissue energy homeostasis

Angiopoietin-like protein 3 (ANGPTL3) is a circulating inhibitor of lipoprotein and endothelial lipase whose physiological function has remained obscure. Here we show that ANGPTL3 plays a major role in promoting uptake of circulating very low density lipoprotein-triglycerides (VLDL-TGs) into white a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Yan, McNutt, Markey C., Banfi, Serena, Levin, Michael G., Holland, William L., Gusarova, Viktoria, Gromada, Jesper, Cohen, Jonathan C., Hobbs, Helen H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577179/
https://ncbi.nlm.nih.gov/pubmed/26305978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515374112
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