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EPS8 phosphorylation by Src modulates its oncogenic functions
BACKGROUND: EPS8 is a scaffolding protein that regulates proliferation, actin dynamics and receptor trafficking. Its expression is increased in cancer, enhancing mitogenesis, migration and tumorigenesis. Src phosphorylates EPS8 at four tyrosine residues, although the function is unknown. Here we inv...
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| Publicado no: | Br J Cancer |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7525440/ https://ncbi.nlm.nih.gov/pubmed/32641864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0976-6 |
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