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Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor

The oncolytic adenovirus (Adv) exhibited poor infection efficiency in tumor cells with low coxsackie and adenovirus receptor (CAR) on the cell surface, which limits the therapeutic efficacy of the Adv-mediated cancer gene therapy. In addition, the abundant adenovirus neutralizing antibodies also abr...

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Dades bibliogràfiques
Publicat a:Front Bioeng Biotechnol
Autors principals: Zhang, Yonghui, Wu, Junyi, Zhang, Hailin, Wei, Jiwu, Wu, Junhua
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525182/
https://ncbi.nlm.nih.gov/pubmed/33042975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.574007
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