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Extracellular Vesicles-Mimetic Encapsulation Improves Oncolytic Viro-Immunotherapy in Tumors With Low Coxsackie and Adenovirus Receptor

The oncolytic adenovirus (Adv) exhibited poor infection efficiency in tumor cells with low coxsackie and adenovirus receptor (CAR) on the cell surface, which limits the therapeutic efficacy of the Adv-mediated cancer gene therapy. In addition, the abundant adenovirus neutralizing antibodies also abr...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Principais autores: Zhang, Yonghui, Wu, Junyi, Zhang, Hailin, Wei, Jiwu, Wu, Junhua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525182/
https://ncbi.nlm.nih.gov/pubmed/33042975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.574007
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