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Pannexin-1 channel “fuels” by releasing ATP from bone marrow cells a state of sterile inflammation required for optimal mobilization and homing of hematopoietic stem cells

An efficient harvest of hematopoietic stem/progenitor cells (HSPCs) after pharmacological mobilization from the bone marrow (BM) into peripheral blood (PB) and subsequent proper homing and engraftment of these cells are crucial for clinical outcomes from hematopoietic transplants. Since extracellula...

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Dettagli Bibliografici
Pubblicato in:Purinergic Signal
Autori principali: Cymer, Monika, Brzezniakiewicz-Janus, Katarzyna, Bujko, Kamila, Thapa, Arjun, Ratajczak, Janina, Anusz, Krzysztof, Tracz, Michał, Jackowska-Tracz, Agnieszka, Ratajczak, Mariusz Z., Adamiak, Mateusz
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524928/
https://ncbi.nlm.nih.gov/pubmed/32533388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09706-1
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