CBFB-MYH11 fusion neoantigen enables T cell recognition and killing of acute myeloid leukemia

Proteins created from recurrent fusion genes like CBFB-MYH11 are prevalent in acute myeloid leukemia (AML), often necessary for leukemogenesis, persistent throughout the disease course, and highly leukemia specific, making them attractive neoantigen targets for immunotherapy. A nonameric peptide der...

Full description

Saved in:
Bibliographic Details
Published in:J Clin Invest
Main Authors: Biernacki, Melinda A., Foster, Kimberly A., Woodward, Kyle B., Coon, Michael E., Cummings, Carrie, Cunningham, Tanya M., Dossa, Robson G., Brault, Michelle, Stokke, Jamie, Olsen, Tayla M., Gardner, Kelda, Estey, Elihu, Meshinchi, Soheil, Rongvaux, Anthony, Bleakley, Marie
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524498/
https://ncbi.nlm.nih.gov/pubmed/32831296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137723
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items