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TCR-based Immunotherapy for Hematologic Malignancies

Adoptive immunotherapy with engineered T cells is at the forefront of cancer treatment. T cells can be engineered to express T cell receptors (TCR) specific for tumor-associated antigens (TAAs) derived from intracellular or cell surface proteins. T cells engineered with TCRs (TCR-T) allow for target...

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Detalhes bibliográficos
Publicado no:Cancer J
Main Authors: Biernacki, Melinda A, Brault, Michelle, Bleakley, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540815/
https://ncbi.nlm.nih.gov/pubmed/31135525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000378
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