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Hypoxia-inducible factors and diabetes

Hypoxia can be defined as a relative deficiency in the amount of oxygen reaching the tissues. Hypoxia-inducible factors (HIFs) are critical regulators of the mammalian response to hypoxia. In normal circumstances, HIF-1α protein turnover is rapid, and hyperglycemia further destabilizes the protein....

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autor principal: Gunton, Jenny E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524477/
https://ncbi.nlm.nih.gov/pubmed/32809974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137556
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