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Hypoxia-inducible factor signaling in pulmonary hypertension

Pulmonary hypertension (PH) is characterized by pulmonary artery remodeling that can subsequently culminate in right heart failure and premature death. Emerging evidence suggests that hypoxia-inducible factor (HIF) signaling plays a fundamental and pivotal role in the pathogenesis of PH. This Review...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Pullamsetti, Soni Savai, Mamazhakypov, Argen, Weissmann, Norbert, Seeger, Werner, Savai, Rajkumar
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598042/
https://ncbi.nlm.nih.gov/pubmed/32881714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137558
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