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Hypoxia-inducible factor signaling in pulmonary hypertension

Pulmonary hypertension (PH) is characterized by pulmonary artery remodeling that can subsequently culminate in right heart failure and premature death. Emerging evidence suggests that hypoxia-inducible factor (HIF) signaling plays a fundamental and pivotal role in the pathogenesis of PH. This Review...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Pullamsetti, Soni Savai, Mamazhakypov, Argen, Weissmann, Norbert, Seeger, Werner, Savai, Rajkumar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598042/
https://ncbi.nlm.nih.gov/pubmed/32881714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137558
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