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Reversal of experimental pulmonary hypertension by PDGF inhibition
Progression of pulmonary hypertension is associated with increased proliferation and migration of pulmonary vascular smooth muscle cells. PDGF is a potent mitogen and involved in this process. We now report that the PDGF receptor antagonist STI571 (imatinib) reversed advanced pulmonary vascular dise...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1236676/ https://ncbi.nlm.nih.gov/pubmed/16200212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24838 |
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